People
Group photo, May 2018. From left to right: Gladys Diaz-Vazquez, Gibert Loiseau, Sam Anderson, Sam Condon, Alessandro Senes, Sam Craven, Kai Cai, Beth Caselle and John Yuan.

Clich here for more lab photos and here for the alumni page.

 
The PI
Alessandro Senes
Associate Professor
Room 415C
senes@wisc.edu
608-890-2584
More info
 
Postdocs
Kai Cai
(joint with the Markley Lab)
PhD: University of Wisconsin-Madison, Biochemistry (Markley Lab)
kcai@wisc.edu
Project: Structural biology of bacterial divisome proteins
Elizabeth Caselle (Beth)
PhD: Syracuse University, Chemistry (Korendovych Lab)
caselle@wisc.edu
Project: Characterization of the soluble domains of the FtsBLQ complex and small molecule screening
CV: [PDF]
 
Graduate Students
Samantha Anderson (Sam)
PhD program in Biochemistry (CIBM trainee)
smanderson26@wisc.edu
Project: Structural prediction of transmembrane oligomeric complexes
Senes lab publications:
  1. Anderson SM*, Mueller BK*, Lange EJ and Senes A "Combination of Cα-H hydrogen bonds and van der Waals packing modulates the stability of GxxxG-mediated dimers in membranes" J Am Chem Soc. 2017 139, 15774-83 (*authors contributed equally) [PDF]
  2. Niemann MCE, Weber H, Hluska T, Leonte G, Anderson SM, Novak O, Senes A, and Werner T. "The cytokinin oxidase/dehydrogenase CKX1 is a membrane-bound protein requiring homooligomerization in the endoplasmic reticulum for its cellular activity" Plant Phys. 2018 176, 2024-39 [PDF]
Samson Condon (Sam)
PhD program in Biochemistry (CIBM trainee)
sgcondon@wisc.edu
Project:Structural prediction of transmembrane oligomeric complexes
Senes lab publications:
  1. Zhang Z, Subramaniam S, Kale J, Liao C, Huang B, Brahmbhatt H, Condon SGF, Lapolla SM, Hays, FA, Ding J, He F, Zhang XC, Li J, Senes A, Andrews DW, Lin J "BH3-in-groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes", EMBO J 2016 35, 208-36 [PDF]
  2. Guo X, Niemi NM, Hutchins PD, Condon SGF, Jochem A, Ulbrich A, Higbee AJ, Russell JD, Senes A, Coon JJ, and Pagliarini DJ "Ptc7p dephosphorylates select mitochondrial proteins to enhance metabolic function" Cell Reports 2017 18, 307-13 [PDF]
  3. :
  4. Condon SGF*, Mahbuba DA*, Armstrong CR, Diaz-Vazquez G, Craven SJ, LaPointe LM, Khadria AS, Chadda R, Crooks JA, Rangarajan N, Weibel DB, Hoskins AA, Robertson JL, Cui Q, Senes A "The FtsLB sub-complex of the bacterial divisome is a tetramer with an uninterrupted FtsL helix linking the transmembrane and periplasmic regions" J. Biol. Chem. 2018 293, 1623-41 (*authors contributed equally) [PDF]
Samuel Craven (Sam)
PhD program in Biochemistry
scraven@wisc.edu
Project: Structural studies of the bacterial divisome
Senes lab publications:
  1. Condon SGF*, Mahbuba DA*, Armstrong CR, Diaz-Vazquez G, Craven SJ, LaPointe LM, Khadria AS, Chadda R, Crooks JA, Rangarajan N, Weibel DB, Hoskins AA, Robertson JL, Cui Q, Senes A "The FtsLB sub-complex of the bacterial divisome is a tetramer with an uninterrupted FtsL helix linking the transmembrane and periplasmic regions" J. Biol. Chem. 2018 293, 1623-41 (*authors contributed equally) [PDF]
Gladys Díaz-Vázquez
PhD program in Biophysics (joint with the Cui lab, AOF Fellow)
diazvazquez@wisc.edu
Project: Molecular dynamic studies of membrane proteins of the bacterial divisome
Senes lab publications:
  1. Condon SGF*, Mahbuba DA*, Armstrong CR, Diaz-Vazquez G, Craven SJ, LaPointe LM, Khadria AS, Chadda R, Crooks JA, Rangarajan N, Weibel DB, Hoskins AA, Robertson JL, Cui Q, Senes A "The FtsLB sub-complex of the bacterial divisome is a tetramer with an uninterrupted FtsL helix linking the transmembrane and periplasmic regions" J. Biol. Chem. 2018 293, 1623-41 (*authors contributed equally) [PDF]
Gilbert Loiseau
PhD program in Biochemistry (AOF Fellow) (CBI Trainee)
loiseau@wisc.edu
Project: Modulating protein signaling using metals as ligands
 
Undergraduate Students
Sara Torres-Robles
Biological SIGNALS SROP (San Diego State University, Chemistry)
sarita.aminta@gmail.com
Lab mentor: Beth Caselle
Collin McFadden
Junior (Computer Science)
cmcfadden@wisc.edu
Lab mentor: Sam Anderson
John Yuan
Senior (Biochemistry)
zyuan49@wisc.edu
 
High School students
 
Alessandro Senes
Associate Professor
Department of Biochemistry - UW-Madison
433 Backcock Dr., Room 419
Madison, WI 53706
office (+1) 608-890-2584
lab. (+1) 608-262-7355